Stage IVb 
TMN Any T, any N, M1 
There is spread to distant organs.

Standard Treatment  Neither radiation nor surgery can cure women with distant metastases, but both are used for local relief of symptoms.
    A number of chemotherapy regimens that are effective in the treatment of metastatic cervical cancer are also used to treat metastatic vaginal cancers—cisplatin, carboplatin and the combinations of mitomycin-C + vincristine + bleomycin + cisplatin and cisplatin + ifosfamide + etoposide .

Five-Year Survival  Less than 10 percent 

Investigational 
• Various doses and combinations of chemotherapeutic drugs are being evaluated, including cisplatin,
  carboplatin, ifosfamide, etoposide, mitomycin-C, 5-FU , vincristine, vinblastine , mitoxantrone , bleomycin and
  methotrexate .